Sunday, April 15, 2012

Vaccine table

Take a look at this table.  This is a table taken from CDC vaccine data showing three of the ingredients in vaccines.  The method of showing that a vaccine has nothing to do with autism is to take a vaccinated population and remove one of the vaccines, one of the lines from the table.  Then when the rate of autism is not significantly different from the normal vaccinated population, that vaccine is declared to have no effect on the autism rate.

But suppose that one of these three ingredients were responsible for the autism rate.  How would removing one of many vaccines from the vaccine schedule significantly affect the autism rate?  It wouldn't.  If one of these three ingredients were responsible for the autism epidemic then not even the excluded vaccine could be exonerated.

The bottom line is that the conclusion that any vaccine has been exonerated by such experiments is invalid.  All such experiments have to be thrown out.  Unfortunately, this is the method that has been used by the med community to "prove" that there is no connection between autism and vaccines.

So much for leaving science to the scientists.

Aluminum Foreign Protein Form-aldehyde
Adenovirus x
Anthrax (Biothrax) x x x
BCG (Tice)
DT (Sanofi) x x x
DTaP (Daptacel) x x x
DTaP (Infanrix) x x x
DTaP (Tripedia) x x x
DTaP-IPV (Kinrix) x x x
DTaP-HepB-IPV (Pediarix) x x x
DTaP-IPV/Hib (Pentacel) x x x
Hib (ActHIB) x x
Hib (Hiberix) x
Hib (PedvaxHIB) x
Hib/Hep B (Convax) x x x
Hep A (Havrix) x x x
Hep A (Vaqta) x x x
Hep B (Engerix-B) x x
Hep B (Recombivax) x x x
HepA/Hep B (Twinrix) x x x
Human Papillomavirus (HPV) (Gardasil) x x
Influenza (Afluria)
Influenza (Fluarrix) x
Influenza (Fluvirin) x Nonylhenol ethoxylate
Influenza (Flulaval) x x
Influenza (Fluzone:  Standard, High-Dose, & Intradermal) x x
Influenza (Flumist) x
Japanese Encephalitis (Ixiaro) x x x
Meningococcal (MCV4-Menactra) x
Meningococcal (MCV4-Menveo) x x
Meningococcal (MPSV4-Menomune) x
MMRV (ProQuad) x
Pneumococcal (PCV12 - Prevnar 13) x x
Polio (IPV - Ipol) x x
Rabies (RabAvert) x phenol
Rotovirus (RotaTeq) x
Rotavirus (Rotarix) x
Smallpox (Vaccinia -  x phenol
Td (Decavac) x x x
Td (Tenivac) x x x
Tdap (Adacel) x x x
Tdap (Boostrix) x x x
Typhoid (inactivated - Typhim V1) phenol
Typhoid (oral - Ty21A) x
Varicella (Varivax) x
Yellow Fever (YF-Vax) x
Zoster (Shingles - Zostavax) x

Monday, September 5, 2011

One year to go

David is now 24 years old.  He is starting on his last year before he will achieve a BS in Electrical Engineering.  He is starting on his senior project where he is working on a robot car with a few other EE students.  He is still doing well and maintaining a high B average.

I have him living in his own apartment.  This is not because I want him out of the house.  It is because I want him to learn all of the things about living by himself that will make him self reliant.  He  has to handle a checkbook and pay bills like the rest of us.  He has to do his own cooking and his own laundry.  He has to keep his apartment clean.

He graduates in May.

Sunday, September 5, 2010

A major change

How many believe in the gluten free, casein free (GFCF) diet?  It did not work for David.  He was on it for about a year without any change.  For me, the GFCF diet is the right idea with the wrong approach.  It works for a small percent of the autistic population, though I have to say that if you have an autistic child who is one of that percentage, it can be a big thing.  My brother's son is an Aspie.  Both he and his wife have told me that the GFCF diet is a real pain to keep up with.  At the same time, it is not nearly as bad as what happens to their son when he gets off the GFCF diet.

I have several problems with the GFCF diet.  It is based on leakage of gluten and casein peptides into the blood stream through the blood gut barrier.  There is evidence for this in the urine samples.  It makes sense to try it because as medical interventions go, a) It does not hurt, b) It is not that expensive, c) It is hard to think of any way it would have side effects, d) With those for whom it does work, the effects can be profound.  On the other hand, are gluten and casein peptides the only peptides that leak into the gut?  And, if the blood-gut barrier is permeable, then what about the blood-brain barrier?  The GFCF diet begs both of those questions.  Yet these two questions could explain why the GFCF diet is effective on some and not on others.  It could also explain why the GFCF diet helps but it does not change the fundamental fact that the child is autistic.

When David was in the seventh grade, I came across a paper that talked about glutathione being in the bile which is secreted by the liver.  Anyone who has read my previous posts knows that I am interested in glutathione and the sulfur amino acid chemistry.  So the question was why does the liver put glutathione in the bile?  It is very seldom that you find the body doing something like this without a reason.  The paper speculated that glutathione is in the bile to preserve the blood-gut barrier.  Put this with the low levels of autistic glutathione and gut leakage it is a reasonable, though unproven hypothesis that low levels of glutathione mean gut leakage which in turn means behavior problems for autistic children.  I don't claim that this is all that autism is.  But being able to take care of one aspect of what autism is can be a positive development.  For this reason, I decided to try having David take glutathione with cod liver oil and fish oil.  The amounts were as follows:

250 mg glutathione
1000 mg fish oil
500 mg cod liver oil

I typically spent 2 hours a night dragging David through his homework.  I had to get David to focus on each problem long enough to recognize what the problem was.  David would read the problem and realize that he did not know the answer.  Then I would turn the page to where the answer was.  Then I would get him to focus on it long enough to read the answer.  More effort would be required to get him to write the answer in a sentence form.  An answer that required three sentences would bring howls of protest.

That was David before the glutathione and fish oil.  After two weeks of being given this each day, David was doing homework by himself.  I can't prove that it was the glutathione and the fish oil that made the change.  At the same time, the change was too dramatic to ignore. 

I don't claim that it will work for others.  But if you should try it, post your results if you will. 

Sunday, March 21, 2010

The miracle that is David

David is autistic.  He still is.  The diagnosis still is, just as would be expected as autism is a lifelong condition.  As a three year old, he had all of the signs:  aphasia, which in his case meant that he could not talk; perseverative behaviors; ritualistic behaviors, sound sensitivity; some touch sensitivity; the autistic lookaway; inability to relate with other children.  And yet, all of this only belied the spark of spirit and intelligence that lay underneath.

At the start of second grade, David suffered a huge setback.  He lost some prodigious math skills, going from add with carry, subtraction with borrow,  negative numbers, getting a grasp of multiplication and division facts to only being able to add past five by counting on his fingers.  His magic ability to look at a word and remember how it was spelled went away.

In fourth grade, a little of his ability in math came back.  David could add and subtract, albeit slowly and only with a struggle.  This progress was offset when at the end of the year, David lost the ability to hold a pencil.  It was a real low in my life and I am sure that it was a real low in David's life as well.  Homework became a 2 - 3 hour ordeal each night when after David came down off the ritalin used to help his stay still in class. 

This lasted through seventh grade when David suddenly started doing his homework by himself.  All of his subjects became easier.  It all happened just as quickly as it had when he suffered his losses in second grade.  From seventh grade, math for him evolved from a near impossible chore to something that he could do.  He took up cross country in high school and went from dead last to the middle of the pack.  He suddenly started being able to touch type.  And he developed a knack for drawing, something he obviously did not get from me.  Still his science was so-so and his English was only passing.  When he graduated, David was off to vocational school.  College was clearly not in the cards.

David did well in vocational school and was able to handle the computer design programs well.  Toward the end of it he announce that he wanted to be an engineer.  My first instinct was to steer him back to the path my wife and I had sent him on.  But when I looked at him I could see that he really meant it.  Still, I did not want him to be crushed if he could not handle a curricula that is heavily laden with math, physics and other science.  He would also have to be able to handle the English courses and other courses that would require writing.  None of my objections dissuaded him.  So we enrolled him in 12 credit hours of  the math classes and physics classes that he would have to take before he could even consider engineering as a career.

We were pleased with David's performance that semester.  He had a B average from that semester.  Okay.  But what about the next semester.  Courses would get tougher.   David had to respond.  And he did.  Each semester he has been getting better so that last semester he was placed on the Dean's list. 

David truly is a walking miracle.  He has gone from not able to add past five without counting on his fingers to being placed on the Dean's list in electrical engineering.  He has learned to draw after losing the ability to hold a pencil.  He has learned to run when his autistic gait made running very hard.

Sunday, January 31, 2010

How a vaccine works

When a vaccine is administered to a child, a weakened or dead form of the virus is injected.  Along with the virus, adjuvants such as aluminum phosphate, aluminum hydroxide, squalene are injected.  The purpose of the adjuvants is to promote an immune reaction.  The hope is that the immune reaction will be against the injected virus.  If the immune system is stimulated, is there any reason why a reaction to other foreign substances could not be triggered?  The real question is given the 26-30 shots that are given, and the number of children of different genetic background, can vaccines be causing the asthma epidemic we have been seeing?

I don't have the answer to this, but neither does the medical community.  If such a thing is happening, the medical community does not want to know.

Saturday, December 19, 2009

Autism's Trigger (Another Misnomer)

There are so many things out in the world about autism that are just plain wrong.  If autism is to gain any treatment inroads these wrong things have to be cleared away.  So let's start with something simple - the word trigger as it is used with respect to autism. 

The medical community likes to use the word trigger with the onset of autism.  The implication is that an event happened that innocently caused the autism onset, much like an icicle falling from a tree might trigger an avalanche.  The word is euphomistic and as such, it has magic.  It means that the onset of autism is a fluke of nature.  Whether it is an icicle falling or a man skiing in the wrong place, it was going to happen anyway.  Nothing is really to blame.  Nobody did anything to cause the child to be autistic.  It is a very safe word. 

The truth is that autism hits children like an incoming mortar round.  In some children, like my son, the damage is relatively mild.  (If you could ever call any case of autism mild)  In other children, they are disabled to the point where they can never care for themselves.  What I am implying is not politically correct.  I am implying that there is brain damage.  The word trigger implies a metamorphosis, like a pupae into a butterfly. 

Of course, I understand that there are genes that make it more likely that a child will develop autism.  For me that means that they are more likely to suffer the damage that causes autism.  And so I prefer the word stroke, even though the symptoms of a stroke are not the same as the symptoms of autism.  I prefer it because when the time comes and we understand how autism occurs, we can do something to prevent it. 

Sunday, December 6, 2009

The problem with autism research

How many studies have been done to prove that there is no link between autism and vaccines.  It has to be a lot.  All of them have been statistical.  All of them reach the conclusion that there is no link between autism and vaccines.  The truly amazing thing is that the first requirement for such a statistical study is a control group.  There has never been a published study that includes the one control group that is needed, the group of unvaccinated children.  This is symptomatic of a mindset which is:

    We know that there is no link between vaccines and autism.  Now let's prove it.

This mindset does two things, it listens to anything that supports the argument that there is no connection between autism and vaccines and it ignores anything that says that there might be a connection between autism and vaccines.  Because of that mindset, the following are given specious arguments:

    The lack of any control group (unvaccinated children) measurement
    The change in the rate of autism
    The numerous documented pre (normal) and post (autistic) vaccine cases

The lack of any control group measurement is a valid criticism.  I have heard that it is too hard.  It would not be ethical.  I have heard mockery.  I have heard that the Japanese MMR study had the control group (they only kept their control group free of the MMR vaccine (which only says that the unique ingredients of the MMR are not responsible for the autism rate).  All of the arguments I have heard for not doing a measurement of the control group are specious.

The change in the rate of autism is said to be because of a change in diagnostics.  I suppose that if you have nothing to fill the void that vaccines so naturally fills, this is just as good as any other explanation.  But I was there when the autism bow wave hit.  My son was at the front of it.  If you want to say that I am not qualified to make that judgement, okay.  Then perhaps you should accept the word of Michael Chez.  In his book, Autism and Its Medical Management, he recounts a meeting of Pediatric Neurologists where a question was asked.  "How many of you were treating autism 20 years ago."  You can guess the rest.  If the autism rate had been the same back then they would have known it.  Autism represents a big change to pediatric practice.  The argument that autism has always been around at the same rate that it exists today is specious.  The change in the autism rate is real.

Post hoc ergo propter hoc.  It is the identification of a logic error that says that just because two things happen one right after the other does not mean that one causes the other.  True.  But the pro-vax side takes this as proof that there is no relationship between autism and vaccines.  It is just as much of a mistake to conclude that it means that there is no relationship as to conclude that there is.  But when there are as many cases of autism following vaccination, post hoc ergo propter hoc sounds flippant.  The relationship between vaccines and autism deserves more than simply pointing out the logic error and calling it wrong (logically it is not wrong, it is inconclusive).  It deserves the measurement of the control group. 

In a previous post, Finally, a small break, I referenced the work of Dr Rosemary Waring that showed that the ability of autistics to process tylenol through the system was far less than the norm.  The mechanism for processing tylenol also handles a long list of other toxins for processing through the kidneys.  If this list includes any of the vaccine ingredients do you think that this thread would be pulled?  No, vaccines have to be protected. 

There have been numerous studies that show leakage across the blood gut barrier.  Does it not make sense that if something causes leakage across the blood gut barrier there may also be leakage across the blood brain barrier.  That possibility was pointed out by Andrew Wakefield.  When Andrew Wakefield dry lab'ed his data he lost any credibility and leakage across the blood gut and blood brain barriers became wrong.  Nobody can touch it any more whether he was right about leakage or not.

The problem with autism research is that it is not scientific.  It never has been.  It is political.  Our children will pay dearly for this.